Abstract: This paper analyze the land use types distribution and change in different topographic regions from 2000to 2010in hilly region by GIS, taking elevation, slope and aspect as topographical factors, based on the remote sensing data and the digital elevation model(DEM). The result indicated that, elevation and slope influence land use types distribution obviously, aspect does not, the advantage distribution regions of cropland and construction land are in elevation below 500m and slope below 5°; the advantage distribution regions of grass land are in elevation beyond 500m and below 1500m and slope beyond 5° and below 15°; the advantage distribution regions of forest are in elevation beyond 800m and slope beyond 5°. Land use types change of cropland to construction land have accounted for a large proportion in regions of elevation below 500m and slope below 5°, land use types change of grass land to forest have the largest proportion in other regions.