Abstract: Natural resources go against to regularly agricultural industry for Guizhou, but original ecology agriculture is an agricultural form which highly matching to the natural resource of Guizhou’s agriculture. It could upgrade Guizhou’s agriculture, improve farmers’ livelihood, forge new look of country, create huge social benefit. Guizhou should develop it to break through the restriction of natural resources and to realize characteristics of the rapid development in agriculture. It needs a professional association to provide a platform for communication, governments to provide policy support and fund investment, enterprises to provide industrial and marketing support, R&D Institutions to provide intellectual and technical support,farmers to provide conscientious production.