Abstract: Based on the meterological data of the 29stations in the upper reaches of Hanjiang River during 1960-2011, linear regressive analysis, Mann-Kendall mutation test, spatial interpolation and analysis of wavelets were applied to analyze the spatio-temporal characteristics of annual mean temperature. Results showed that:(1) the annual mean temperature showed an increasing trend, rising at the rates of 0.104℃/10a. Anomaly of air temperature had mainly positive value after 1997, especially annual mean temperature had an obvious increasing trend in the 2000-2007. (2) The mutation year of annual mean temperature was 1997in the upper reaches of Hanjiang River. (3)There was obvious cycle change of annual mean temperature in the areas. 29a is the first main cycle, which is the most powerful oscillation. (4)The spatial distributions of annual mean temperature in the areas display that the lower temperature is in the southern and northern area, but the higher temperature in the middle area, which are distributed along the latitudinal. Compared with 1997years ago, the annual mean temperature of the county showed an increasing trend, but cool and warm center have certain changed after 1997. Especially the range and strength of warm center had enlarged and deepened, the range and strength of cold center had narrowed and weakened after 1997. (5) According to the change of temperature trend rate, the temperature increased less or decreased slightly in the middle valley basin area with higher annual mean temperature, but increased obviously in north and south valley area with lower temperature. And warm center have moved from east higher temperature area to west lower temperature area in the Upper reaches of Hanjiang around 1997.